Ikzf1^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Ikzf1^m1Btlr
• Name: IKAROS family zinc finger 1; mutation 1, Bruce Beutler
• MGI ID: MGI:6200316
• Synonyms: star_lord
• Gene: Ikzf1 Location: Chr11:11634980-11722926 bp, + strand Genetic Position: Chr11, 7.02 cM
• Alliance: Ikzf1^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced T to A transversion at base pair 11,769,448 (v38) on chromosome 11, or base pair 84,479 in the GenBank genomic region NC_000077 encoding Ikzf1. The mutation corresponds to residue 1,972 in the mRNA sequence NM_001025597 within exon 8 of 8 total exons. The mutation results in a methionine to lysine substitution at amino acid 472 (M472K) in variant 1 of the IKZF1 protein. (J:265249)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ikzf1 Mutation: 30 strains or lines available

References

• Original: J:265249 Teixeira S, et al., Mutagenetix entry for star_lord. MGI Direct Data Submission. 2018
• All: 1 reference(s)