Ikzf1^m3Btlr
Chemically induced Allele Detail

Summary

• Symbol: Ikzf1^m3Btlr
• Name: IKAROS family zinc finger 1; mutation 3, Bruce Beutler
• MGI ID: MGI:6200327
• Synonyms: herrscher
• Gene: Ikzf1 Location: Chr11:11634980-11722926 bp, + strand Genetic Position: Chr11, 7.02 cM
• Alliance: Ikzf1^m3Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced C to T transition at base pair 11,768,961(v38) on chromosome 11, or base pair 83,993 in the GenBank genomic region NC_000077 encoding Ikzf1. The mutation corresponds to residue 1,486 in the mRNA sequence NM_001025597 within exon 8 of 8 total exons. The mutation results in substitution of glutamine 310 for a premature stop codon (Q310*) in variant 1 of the IKZF1 protein. (J:265251)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ikzf1 Mutation: 30 strains or lines available

References

• Original: J:265251 Zhong X, et al., Mutagenetix entry for herrscher. MGI Direct Data Submission. 2018
• All: 1 reference(s)