Edar^dl-2Btlr
Chemically induced Allele Detail

Summary

• Symbol: Edar^dl-2Btlr
• Name: ectodysplasin-A receptor; downless 2 Bruce Beutler
• MGI ID: MGI:6200340
• Synonyms: two-tone
• Gene: Edar Location: Chr10:58436611-58511476 bp, - strand Genetic Position: Chr10, 29.37 cM, cytoband B3
• Alliance: Edar^dl-2Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced A to T transversion at base pair 58,603,179 (v38) on chromosome 10, or base pair 72,518 in the GenBank genomic region NC_000076.6. The mutation corresponds to residue 1,289 in the mRNA sequence NM_010100 within exon 12 of 12 total exons. The mutation results in a serine to cysteine substitution at position 344 (S344C) in the EDAR protein. (J:265254)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Edar Mutation: 30 strains or lines available

References

• Original: J:265254 Keef J, et al., Mutagenetix entry for two-tone. MGI Direct Data Submission. 2018
• All: 1 reference(s)