Rasgrp1^m3Btlr
Chemically induced Allele Detail

Summary

• Symbol: Rasgrp1^m3Btlr
• Name: RAS guanyl releasing protein 1; mutation 3, Bruce Beutler
• MGI ID: MGI:6200346
• Synonyms: naejangsan
• Gene: Rasgrp1 Location: Chr2:117110464-117173358 bp, - strand Genetic Position: Chr2, 59.19 cM
• Alliance: Rasgrp1^m3Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced T to A transversion at base pair 117,291,792 (v38) on chromosome 2, or base pair 51,086 in the GenBank genomic region NC_000068 encoding Rasgrp1. The mutation corresponds to residue 1,284 in the mRNA sequence NM_011246 within exon 9 of 17 total exons. The mutation results in substitution of tyrosine 372 for a premature stop codon (Y372*). (J:265255)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rasgrp1 Mutation: 57 strains or lines available

References

• Original: J:265255 Zhong X, et al., Mutagenetix entry for naejangsan. MGI Direct Data Submission. 2018
• All: 1 reference(s)