Gys2^m2Btlr
Chemically induced Allele Detail

Summary

• Symbol: Gys2^m2Btlr
• Name: glycogen synthase 2; mutation 2, Bruce Beutler
• MGI ID: MGI:6200360
• Synonyms: embittered
• Gene: Gys2 Location: Chr6:142368339-142418835 bp, - strand Genetic Position: Chr6, 74.04 cM
• Alliance: Gys2^m2Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced T to A transversion at base pair 142,454,484 (v38) on chromosome 6, or base pair 18,647 in the GenBank genomic region NC_000072 encoding Gys2. The mutation corresponds to residue 1,308 in the mRNA sequence NM_145572 within exon 7 of 17 total exons. The mutation results in a phenylalanine (F) to isoleucine (I) substitution at residue 334 (F334I) in the GYS2 protein. (J:265257)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gys2 Mutation: 45 strains or lines available

References

• Original: J:265257 Turer E, et al., Mutagenetix entry for embittered. MGI Direct Data Submission. 2018
• All: 1 reference(s)