Ly96^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Ly96^m1Btlr
• Name: lymphocyte antigen 96; mutation 1, Bruce Beutler
• MGI ID: MGI:6200370
• Synonyms: pique
• Gene: Ly96 Location: Chr1:16758680-16779829 bp, + strand Genetic Position: Chr1, 5.1 cM
• Alliance: Ly96^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced G to T transversion at base pair 16,691,716 (v38) on chromosome 1, or base pair 3,261 in the GenBank genomic region NC_000067 encoding Ly96. The mutation corresponds to residue 197 in the mRNA sequence NM_016923 within exon 2 of 5 total exons. The mutation results in substitution of glutamic acid 49 (E49) for a premature stop codon (E49*) in the MD-2 protein. (J:265259)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ly96 Mutation: 13 strains or lines available

References

• Original: J:265259 Ochoa C, et al., Mutagenetix entry for pique. MGI Direct Data Submission. 2018
• All: 1 reference(s)