Haspin^tm1Htan
Targeted Allele Detail

Summary

• Symbol: Haspin^tm1Htan
• Name: histone H3 associated protein kinase; targeted mutation 1, Hiromitsu Tanaka
• MGI ID: MGI:6203625
• Synonyms: Haspin^tm1Mkt
• Gene: Haspin Location: Chr11:73026311-73029120 bp, - strand Genetic Position: Chr11, 45.25 cM
• Alliance: Haspin^tm1Htan page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:240842
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• The entire open reading frame was replaced with a neo cassette via homologous recombination. (J:240842)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Haspin Mutation: 26 strains or lines available

References

• Original: J:240842 Shimada M, et al., Essential role of autoactivation circuitry on Aurora B-mediated H2AX-pS121 in mitosis. Nat Commun. 2016 Jul 08;7:12059
• All: 1 reference(s)