Niban2^em1(IMPC)J
Endonuclease-mediated Allele Detail

Summary

• Symbol: Niban2^em1(IMPC)J
• Name: niban apoptosis regulator 2; endonuclease-mediated mutation 1, Jackson
• MGI ID: MGI:6214829
• Gene: Niban2 Location: Chr2:32766146-32815265 bp, + strand Genetic Position: Chr2, 22.09 cM
• Alliance: Niban2^em1(IMPC)J page
• IMPC: Niban2 gene page

Mutation origin

• Strain of Origin: C57BL/6NJ
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences ATATCCTTTCACACAAACCG and GAGACCAAACCAGCAGCATA, which resulted in a 626 bp deletion beginning at Chromosome 2 position 32,905,645 bp and ending after 32,906,270 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000388163 (exon 2) and 495 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 18 and early truncation 4 amino acids later. (J:188991)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Niban2 Mutation: 55 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 2 reference(s)