Traj18^em1Hwata
Endonuclease-mediated Allele Detail

Summary

• Symbol: Traj18^em1Hwata
• Name: T cell receptor alpha joining 18; endonuclease-mediated mutation 1, Hiroshi Watarai
• MGI ID: MGI:6220718
• Synonyms: Traj18^- (1-1L)
• Gene: Traj18 Location: Chr14:54438234-54438299 bp, + strand Genetic Position: Chr14, 27.69 cM
• Alliance: Traj18^em1Hwata page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology generated a partial deletion. (J:256533)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Traj18 Mutation: 4 strains or lines available

References

• Original: J:256533 Ren Y, et al., A Novel Mouse Model of iNKT Cell-deficiency Generated by CRISPR/Cas9 Reveals a Pathogenic Role of iNKT Cells in Metabolic Disease. Sci Rep. 2017 Oct 6;7(1):12765
• All: 1 reference(s)