Dcaf13^em1Hyfn
Endonuclease-mediated Allele Detail

Summary

• Symbol: Dcaf13^em1Hyfn
• Name: DDB1 and CUL4 associated factor 13; endonuclease-mediated mutation 1, Heng-Yu Fan
• MGI ID: MGI:6256448
• Gene: Dcaf13 Location: Chr15:38976300-39010251 bp, + strand Genetic Position: Chr15, 15.42 cM
• Alliance: Dcaf13^em1Hyfn page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• TALEN-targeting introduced an 8 bp deletion and frame-shift mutation within exon 2. (J:266543)

Expression

In Mice Carrying this Mutation:	10 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dcaf13 Mutation: 42 strains or lines available

References

• Original: J:266543 Zhang YL, et al., DCAF13 promotes pluripotency by negatively regulating SUV39H1 stability during early embryonic development. EMBO J. 2018 Sep 14;37(18)
• All: 1 reference(s)