Usp34^em1Qyn
Endonuclease-mediated Allele Detail

Summary

• Symbol: Usp34^em1Qyn
• Name: ubiquitin specific peptidase 34; endonuclease-mediated mutation 1, Quan Yuan
• MGI ID: MGI:6256462
• Synonyms: Usp34^f
• Gene: Usp34 Location: Chr11:23256895-23440560 bp, + strand Genetic Position: Chr11, 14.29 cM
• Alliance: Usp34^em1Qyn page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• CRISPR-targeting flanked exon 2 with loxP sites. (J:266454)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Usp34 Mutation: 190 strains or lines available

References

• Original: J:266454 Guo YC, et al., Ubiquitin-specific protease USP34 controls osteogenic differentiation and bone formation by regulating BMP2 signaling. EMBO J. 2018 Oct 15;37(20)
• All: 2 reference(s)