Sall4^{tm1.1(EGFP/cre/ERT2)Ykawa}
Targeted Allele Detail

Summary

• Symbol: Sall4^{tm1.1(EGFP/cre/ERT2)Ykawa}
• Name: spalt like transcription factor 4; targeted mutation 1.1, Yasuhiko Kawakami
• MGI ID: MGI:6257344
• Synonyms: Sall4 GCE
• Gene: Sall4 Location: Chr2:168590252-168609121 bp, - strand Genetic Position: Chr2, 88.99 cM
• Alliance: Sall4^{tm1.1(EGFP/cre/ERT2)Ykawa} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:266804
• Parent Cell Line: G4 (ES Cell)
• Strain of Origin: (129S6/SvEvTac x C57BL/6NCrl)F1

Mutation description

• Allele Type: Targeted (Inducible, Null/knockout, Recombinase, Reporter)
• Inducer: tamoxifen
• Mutations: Insertion, Intragenic deletion
• Sall4^{tm1.1(EGFP/cre/ERT2)Ykawa} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Sall4 (MGI:2139360)

• Mutation details: Sall4 exon1 was replaced with the GFP-Cre-ERT2 cassette followed by an frt flanked neo cassette via homologous recombination. Resulting mice were bred with Flpo mouse line to eliminate the neo cassette. (J:101977, J:266804)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Sall4 (mouse) Summary of all recombinase alleles driven by Sall4. Comparative matrix view of recombinase activities Alliance mouse Sall4 gene page

Expression

In Mice Carrying this Mutation:

24 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Sall4 Mutation: 145 strains or lines available

References

• Original: J:266804 Tahara N, et al., Temporal changes of Sall4 lineage contribution in developing embryos and the contribution of Sall4-lineages to postnatal germ cells in mice. Sci Rep. 2018 Nov 6;8(1):16410
• All: 2 reference(s)