Msto1^em1(IMPC)Tcp
Endonuclease-mediated Allele Detail

Summary

• Symbol: Msto1^em1(IMPC)Tcp
• Name: misato 1, mitochondrial distribution and morphology regulator; endonuclease-mediated mutation 1, The Centre for Phenogenomics
• MGI ID: MGI:6257438
• Gene: Msto1 Location: Chr3:88816923-88821257 bp, - strand Genetic Position: Chr3, 39.01 cM
• Alliance: Msto1^em1(IMPC)Tcp page
• IMPC: Msto1 gene page

Mutation origin

• Strain of Origin: C57BL/6NCrl
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele from project TCPR1154 was generated at The Centre for Phenogenomics by electroporating Cas9 ribonucleoprotein complexes with single guide RNAs having spacer sequences of GACTAAACTGATCACCTGTC targeting the 5' side and GCTCTCCGATGCACAGTAAA targeting the 3' side of a critical exon. This resulted in a 376-bp del Chr3:88912622 to 88912997_insT (GRCm38). (J:265051)
• Inheritance: Not Specified

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Msto1 Mutation: 32 strains or lines available

References

• Original: J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023
• All: 3 reference(s)