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Atp5f1dem1(IMPC)Bay
Endonuclease-mediated Allele Detail
Summary
Symbol: Atp5f1dem1(IMPC)Bay
Name: ATP synthase F1 subunit delta; endonuclease-mediated mutation 1, Baylor College of Medicine
MGI ID: MGI:6257672
Synonyms: Atp5f1d-
Gene: Atp5f1d  Location: Chr10:79974466-79981652 bp, + strand  Genetic Position: Chr10, 39.72 cM, cytoband C1
Alliance: Atp5f1dem1(IMPC)Bay page
IMPC: Atp5f1d gene page
Atp5f1dem1(IMPC)Bay/Atp5f1dem1(IMPC)Bay mice exhibit embryonic lethality, with embryos recovered at E3.5 as blastocysts but not at E7.5. Blastocysts fail to hatch from the zona pellucida after 3 days in culture.

Show the 1 phenotype image(s) involving this allele.

Mutation
origin
Strain of Origin:  C57BL/6N
Project Collection: IMPC
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsThis allele from IMPC was generated at Bayor College of Medicine by injecting CAS9 Protein and 4 guide sequences CCTCATAGCAACTTCCTGAGTGG, CCAGGGGCTGGATCAGCACGCTG, GGGTAAGATAGCCTTGGTGTAGG, CCTTTAGGGTAAGATAGCCTTGG, which resulted in a Exon Deletion. (J:265051)
Inheritance:    Not Specified
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Atp5f1d Mutation:  6 strains or lines available
References
Original:  J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023;
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory