Rnf113a1^em1(IMPC)Tcp
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rnf113a1^em1(IMPC)Tcp
• Name: ring finger protein 113A1; endonuclease-mediated mutation 1, The Centre for Phenogenomics
• MGI ID: MGI:6257832
• Gene: Rnf113a1 Location: ChrX:36454898-36456120 bp, + strand Genetic Position: ChrX, 21.61 cM
• Alliance: Rnf113a1^em1(IMPC)Tcp page
• IMPC: Rnf113a1 gene page

Mutation origin

• Strain of Origin: C57BL/6NCrl
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele from project TCPR1341 was generated at The Centre for Phenogenomics by electroporating Cas9 ribonucleoprotein complexes with single guide RNAs having spacer sequences of TCCCGGGAATTCTACCCGTC and CGTCTACAAGTCTACCCGTT targeting the 5' side and GGCTGGATTAAAGACGCCAT targeting the 3' side of a critical region. This resulted in a 873-bp deletion of Chrx from 37191426 to 37192298 (GRCm38). (J:265051)
• Inheritance: Not Specified

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Rnf113a1 Mutation: 8 strains or lines available

References

• Original: J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023
• All: 3 reference(s)