Mlf1^tm1Swm
Targeted Allele Detail

Summary

• Symbol: Mlf1^tm1Swm
• Name: myeloid leukemia factor 1; targeted mutation 1, Stephan W Morris
• MGI ID: MGI:6257884
• Gene: Mlf1 Location: Chr3:67281430-67307333 bp, + strand Genetic Position: Chr3, 30.91 cM
• Alliance: Mlf1^tm1Swm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:266833
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A portion of exon 2 was replaced by stop codons and a neomycin selection cassette. (J:266833)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mlf1 Mutation: 21 strains or lines available

References

• Original: J:266833 Sun Y, et al., Myeloid leukemia factor 1 interfered with Bcl-XL to promote apoptosis and its function was regulated by 14-3-3. J Physiol Biochem. 2015 Dec;71(4):807-21
• All: 2 reference(s)