Sox30^em2Hncs
Endonuclease-mediated Allele Detail

Summary

• Symbol: Sox30^em2Hncs
• Name: SRY (sex determining region Y)-box 30; endonuclease-mediated mutation 2, Chunsheng Han
• MGI ID: MGI:6258440
• Gene: Sox30 Location: Chr11:45871137-45908821 bp, + strand Genetic Position: Chr11, 27.49 cM
• Alliance: Sox30^em2Hncs page

Mutation origin

• Strain of Origin: C57BL/6J x DBA

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR-targeting of exon 1 deleted 209 bp. The deletion is predicted it truncate the protein at amino acid 255 due to a frameshift. (J:264140)

Expression

In Mice Carrying this Mutation:	2 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sox30 Mutation: 19 strains or lines available

References

• Original: J:264140 Zhang D, et al., The transcription factor SOX30 is a key regulator of mouse spermiogenesis. Development. 2018 May 30;145(11):dev164723
• All: 1 reference(s)