Afmid^em1Llp
Endonuclease-mediated Allele Detail

Summary

• Symbol: Afmid^em1Llp
• Name: arylformamidase; endonuclease-mediated mutation 1, Luanne Peters
• MGI ID: MGI:6259101
• Gene: Afmid Location: Chr11:117716750-117730734 bp, + strand Genetic Position: Chr11, 82.96 cM, cytoband E2
• Alliance: Afmid^em1Llp page
• IMPC: Afmid gene page

Mutation origin

• Strain of Origin: C57BL/6NJ
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated by Dr. Luanne Peters at The Jackson Laboratory by microinjection of Cas9 mRNA and 2 guide sequences, GACATCTACTTTCCCGATG and CCAGCTGGATGTCCCCTA, which resulted in a 42 bp deletion beginning at approximately Chromosome 11 position 117,832,392 bp, TATGGAGAT, and ending after 117,832,433 bp, TTTCCC (GRCm38/mm10). This mutation deletes much of exon 3. (J:188991)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Afmid Mutation: 38 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 3 reference(s)