Tspan13^em1Llp
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tspan13^em1Llp
• Name: tetraspanin 13; endonuclease-mediated mutation 1, Luanne Peters
• MGI ID: MGI:6259149
• Gene: Tspan13 Location: Chr12:36064554-36092477 bp, - strand Genetic Position: Chr12, 16.25 cM, cytoband B2
• Alliance: Tspan13^em1Llp page
• IMPC: Tspan13 gene page

Mutation origin

• Strain of Origin: C57BL/6NJ
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated by Dr. Luanne Peters at The Jackson Laboratory by microinjection of Cas9 mRNA and 4 guide sequences, CATTGGGATTGCTGCCTG, ATGACCACACCCACCACT, CTCCAATTAGCCCCACCA, and AAAAATAGCAACACCTGG, which resulted in a 101 bp deletion beginning at approximately Chromosome 12 negative strand position 36,024,049 bp, ATTGCT, and ending after 36,023,947 bp, CCTGAT (GRCm38.p6/mm10). This mutation deletes much of ENSMUSG00000020577 (exon 2). (J:188991)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Tspan13 Mutation: 14 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 2 reference(s)