Wdr70em1(IMPC)J
Endonuclease-mediated Allele Detail
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Symbol: |
Wdr70em1(IMPC)J |
Name: |
WD repeat domain 70; endonuclease-mediated mutation 1, Jackson |
MGI ID: |
MGI:6259591 |
Gene: |
Wdr70 Location: Chr15:7902536-8128693 bp, - strand Genetic Position: Chr15, 3.82 cM
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Alliance: |
Wdr70em1(IMPC)J page
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IMPC: |
Wdr70 gene page |
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Strain of Origin: |
C57BL/6NJ
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Project Collection: |
IMPC
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Allele Type: |
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Endonuclease-mediated (Null/knockout) |
Mutation: |
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Intragenic deletion
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Mutation details: This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences GCTGGGGATCTTGTGATACA and CATCTGGAATGGAATCCCCC, which resulted in a 453 bp deletion beginning at Chromosome 15 position 8,082,304 bp and ending after 8,082,756 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000564027 (exon 4) and 332 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 58 and early truncation 20 amino acids later.
(J:188991)
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Inheritance: |
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Not Specified |
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Original: |
J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012; |
All: |
2 reference(s) |
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