Lrp4^em1Krum
Endonuclease-mediated Allele Detail

Summary

• Symbol: Lrp4^em1Krum
• Name: low density lipoprotein receptor-related protein 4; endonuclease-mediated mutation 1, Robb Krumlauf
• MGI ID: MGI:6259817
• Synonyms: Lrp4^LacZ
• Gene: Lrp4 Location: Chr2:91287856-91344124 bp, + strand Genetic Position: Chr2, 50.63 cM
• Alliance: Lrp4^em1Krum page

Mutation origin

• Strain of Origin: (C57BL/10J x CBA/J)F2

Mutation description

• Allele Type: Endonuclease-mediated (Reporter)
• Mutation: Insertion
• CRISPR-targeting inserted a lacZ reporter gene into the first exon. (J:243416)

Expression

In Mice Carrying this Mutation:

8 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lrp4 Mutation: 97 strains or lines available

References

• Original: J:243416 Ahn Y, et al., Multiple modes of Lrp4 function in modulation of Wnt/beta-catenin signaling during tooth development. Development. 2017 Aug 01;144(15):2824-2836
• All: 1 reference(s)