H2bc21^em1(IMPC)Bay
Endonuclease-mediated Allele Detail

Summary

• Symbol: H2bc21^em1(IMPC)Bay
• Name: H2B clustered histone 21; endonuclease-mediated mutation 1, Baylor College of Medicine
• MGI ID: MGI:6266818
• Gene: H2bc21 Location: Chr3:96128435-96131054 bp, + strand Genetic Position: Chr3, 41.67 cM, cytoband F1-F2
• Alliance: H2bc21^em1(IMPC)Bay page
• IMPC: H2bc21 gene page

Mutation origin

• Strain of Origin: C57BL/6N
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Deletion
• Mutation details: This allele from IMPC was generated at Bayor College of Medicine by injecting CAS9 Protein and 4 guide sequences CCTGGATGAGGCGCTCGCTGGCC, GCTTTTAATCATGCCTGAACTGG, CCAGCGCCAAGTAGAGGCCTCCC, TCTGCCCCGGCTCCCAAGAAGGG, which resulted in a Whole-gene deletion. (J:265051)
• Inheritance: Not Specified

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any H2bc21 Mutation: 12 strains or lines available

References

• Original: J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023
• All: 3 reference(s)