Tg(Dct-Hes1)#Nshk
Transgene Detail

Summary

• Symbol: Tg(Dct-Hes1)#Nshk
• Name: transgene insertion, Shin-Ichi Nishikawa
• MGI ID: MGI:6267303
• Synonyms: Dct-Hes1
• Transgene: Tg(Dct-Hes1)#Nshk Location: unknown
• Alliance: Tg(Dct-Hes1)#Nshk page

Attenuation of DAPT-induced apoptosis in Tg(Dct-Hes1)#Nshk/0 skin

Show the 1 phenotype image(s) involving this allele.

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Dct-Hes1)#Nshk expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Hes1 (MGI:104853)

• Mutation details: This transgene contains the Dct (dopamine tautomerase) promoter driving melanoblast-specific expression of the mouse Hes1 gene. RT-PCR analysis confirmed specific transgene expression in melanoblasts. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:111228)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:111228 Moriyama M, et al., Notch signaling via Hes1 transcription factor maintains survival of melanoblasts and melanocyte stem cells. J Cell Biol. 2006 May 8;173(3):333-9
• All: 1 reference(s)