Miox^tm1Ysk
Targeted Allele Detail

Summary

• Symbol: Miox^tm1Ysk
• Name: myo-inositol oxygenase; targeted mutation 1, Yashpal S Kanwar
• MGI ID: MGI:6267379
• Gene: Miox Location: Chr15:89218676-89221210 bp, + strand Genetic Position: Chr15, 44.82 cM
• Alliance: Miox^tm1Ysk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:266834
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEv

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 2. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 10. (J:266834)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Miox Mutation: 37 strains or lines available

References

• Original: J:266834 Dutta RK, et al., Beneficial Effects of Myo-Inositol Oxygenase Deficiency in Cisplatin-Induced AKI. J Am Soc Nephrol. 2017 May;28(5):1421-1436
• All: 6 reference(s)