Tg(CAG-lacZ,-Miox)#Ysk
Transgene Detail

Summary

• Symbol: Tg(CAG-lacZ,-Miox)#Ysk
• Name: transgene insertion, Yashpal S Kanwar
• MGI ID: MGI:6267411
• Synonyms: CBA-flox
• Transgene: Tg(CAG-lacZ,-Miox)#Ysk Location: unknown
• Alliance: Tg(CAG-lacZ,-Miox)#Ysk page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Conditional ready, Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Mutation details: A CMV-chicken beta-actin hybrid promoter (CAG; also refered to as CBA in publication) with the cytomegalovirus immediate early enhancer linked to the beta actin proomoter and a chimeric intron of beta-globin and immunoglobin genes drives ubiquitous expression of the mouse cDNA preceeded by a floxed beta-gal-STOP-codon cassette. The pound symbol is used when no line is specified and/or lines are pooled. (J:266834)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:266834 Dutta RK, et al., Beneficial Effects of Myo-Inositol Oxygenase Deficiency in Cisplatin-Induced AKI. J Am Soc Nephrol. 2017 May;28(5):1421-1436
• All: 6 reference(s)