Asf1b^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Asf1b^m1Btlr
• Name: anti-silencing function 1B histone chaperone; mutation 1, Bruce Beutler
• MGI ID: MGI:6268351
• Synonyms: contraire
• Gene: Asf1b Location: Chr8:84682323-84696824 bp, + strand Genetic Position: Chr8, 40.22 cM
• Alliance: Asf1b^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced T to C transition at base pair 83,955,911 (v38) on chromosome 8, or base pair 218 in the GenBank genomic region NC_000074 encoding Asf1b. The mutation corresponds to residue 218 in the mRNA sequence NM_024184 within exon 1 of 4 total exons. The mutated nucleotide is indicated in red. The mutation results in a phenylalanine to serine substitution at position 28 (F28S) in the ASF1B protein. (J:267479)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Asf1b Mutation: 20 strains or lines available

References

• Original: J:267479 Nair-Gill E, et al., Mutagenetix entry for contraire. MGI Direct Data Submission. 2018
• All: 1 reference(s)