Gamt^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Gamt^m1Btlr
• Name: guanidinoacetate methyltransferase; mutaiton 1, Bruce Beutler
• MGI ID: MGI:6268363
• Synonyms: mr_bigger
• Gene: Gamt Location: Chr10:80093985-80096846 bp, - strand Genetic Position: Chr10, 39.72 cM
• Alliance: Gamt^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced A to T transversion at base pair 80,260,724 (v38) on chromosome 10, or base pair 303 in the GenBank genomic region NC_000076 encoding Gamt. The mutation corresponds to residue 289 in the mRNA sequence NM_010255 within exon 1 of 6 total exons. The mutation results in substitution of arginine 60 to a premature stop codon (R60*) in the GAMT protein. (J:267482)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gamt Mutation: 11 strains or lines available

References

• Original: J:267482 Turer E, et al., Mutagenetix entry for mr_bigger. MGI Direct Data Submission. 2018
• All: 1 reference(s)