Cd44^M1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Cd44^M1Btlr
• Name: CD44 antigen; mutation 1, Bruce Beutler
• MGI ID: MGI:6268367
• Synonyms: Jialin
• Gene: Cd44 Location: Chr2:102641486-102732010 bp, - strand Genetic Position: Chr2, 54.13 cM
• Alliance: Cd44^M1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced G to T transversion at base pair 102,865,370 (v38) on chromosome 2, or base pair 36,300 in the GenBank genomic region NC_000068 encoding Cd44. The mutation corresponds to residue 475 in the mRNA sequence NM_009851 within exon 2 of 19 total exons. The mutation results in a glutamic acid (E) to aspartic acid (D) substitution at position 52 (E52D) in the CD44 protein. (J:267483)
• Inheritance: Dominant

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cd44 Mutation: 72 strains or lines available

References

• Original: J:267483 Zhong X, et al., Mutagenetix entry for Jialin. MGI Direct Data Submission. 2018
• All: 1 reference(s)