Myo1dm4Btlr
Chemically induced Allele Detail
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Symbol: |
Myo1dm4Btlr |
Name: |
myosin ID; mutation 4, Bruce Beutler |
MGI ID: |
MGI:6268408 |
Synonyms: |
whisper3 |
Gene: |
Myo1d Location: Chr11:80372952-80670851 bp, - strand Genetic Position: Chr11, 47.95 cM
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Alliance: |
Myo1dm4Btlr page
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Strain of Origin: |
C57BL/6J
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Project Collection: |
Beutler Mutagenetix
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Allele Type: |
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Chemically induced (ENU) (Not Specified) |
Mutation: |
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Single point mutation
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Mutation details: ENU-induced A to T transversion at base pair 80,557,521 (v38) on chromosome 11 corresponding to base pair 222,535 in the GenBank genomic region NC_000077 encoding Myo1d. The mutation corresponds to residue 3,010 in the mRNA sequence NM_177390 within exon 21 of 22 total exons. residue 218 in the mRNA sequence NM_024184 within exon 1 of 4 total exons. The mutation results in an aspartic acid to valine substitution at position 926 (D926V) in the Myo1d protein.
(J:267525)
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Inheritance: |
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Recessive |
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Myo1d Mutation: |
61 strains or lines available
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Original: |
J:267525 McAlpine W, et al., The class I myosin MYO1D binds to lipid and protects against colitis. Dis Model Mech. 2018 Sep 27;11(9):dmm035923 |
All: |
1 reference(s) |
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