About   Help   FAQ
Myo1dm4Btlr
Chemically induced Allele Detail
Summary
Symbol: Myo1dm4Btlr
Name: myosin ID; mutation 4, Bruce Beutler
MGI ID: MGI:6268408
Synonyms: whisper3
Gene: Myo1d  Location: Chr11:80372952-80670851 bp, - strand  Genetic Position: Chr11, 47.95 cM
Alliance: Myo1dm4Btlr page
Mutation
origin
Strain of Origin:  C57BL/6J
Project Collection: Beutler Mutagenetix
Mutation
description
Allele Type:    Chemically induced (ENU) (Not Specified)
Mutation:    Single point mutation
 
Mutation detailsENU-induced A to T transversion at base pair 80,557,521 (v38) on chromosome 11 corresponding to base pair 222,535 in the GenBank genomic region NC_000077 encoding Myo1d. The mutation corresponds to residue 3,010 in the mRNA sequence NM_177390 within exon 21 of 22 total exons. residue 218 in the mRNA sequence NM_024184 within exon 1 of 4 total exons. The mutation results in an aspartic acid to valine substitution at position 926 (D926V) in the Myo1d protein. (J:267525)
Inheritance:    Recessive
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Myo1d Mutation:  61 strains or lines available
References
Original:  J:267525 McAlpine W, et al., The class I myosin MYO1D binds to lipid and protects against colitis. Dis Model Mech. 2018 Sep 27;11(9):dmm035923
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
11/12/2024
MGI 6.24
The Jackson Laboratory