Fgf3^M1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Fgf3^M1Btlr
• Name: fibroblast growth factor 3; mutation 1, Bruce Beutler
• MGI ID: MGI:6268746
• Synonyms: Porkchop
• Gene: Fgf3 Location: Chr7:144392349-144397085 bp, + strand Genetic Position: Chr7, 88.85 cM
• Alliance: Fgf3^M1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Insertion
• Mutation details: ENU-induced T to C transition at base pair 144,840,707 (v38) on chromosome 7, or base pair 2,751 in the GenBank genomic region NC_000073 encoding Fgf3. The mutation corresponds to residue 353 in the mRNA sequence NM_008007 within exon 2 of 3 total exons. The mutation results in a valine to alanine substitution at amino acid 86 (V86A) in the FGF3 protein. (J:267538)
• Inheritance: Dominant

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fgf3 Mutation: 16 strains or lines available

References

• Original: J:267538 Ludwig S, et al., Mutagenetix entry for Porkchop. MGI Direct Data Submission. 2018
• All: 1 reference(s)