Nek8^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Nek8^m1Btlr
• Name: NIMA (never in mitosis gene a)-related expressed kinase 8; mutation 1, Bruce Beutler
• MGI ID: MGI:6268750
• Synonyms: nerkkod
• Gene: Nek8 Location: Chr11:78056932-78067501 bp, - strand Genetic Position: Chr11, 46.74 cM, cytoband B5
• Alliance: Nek8^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced T to C transition at base pair 78,173,059 (v38) on chromosome 11, or base pair 3,641 in the GenBank genomic region NC_000077. The mutation corresponds to residue 179 in the mRNA sequence NM_080849 within exon 2 of 15 total exons. The mutation results in a methionine to threonine substitution at position 40 (M40T) in the NEK8 protein. (J:267544)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nek8 Mutation: 28 strains or lines available

References

• Original: J:267544 Pontes R, et al., Mutagenetix entry for nerkkod. MGI Direct Data Submission. 2018
• All: 1 reference(s)