Gimap1^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Gimap1^m1Btlr
• Name: GTPase, IMAP family member 1; mutation 1, Bruce Beutler
• MGI ID: MGI:6268754
• Synonyms: vonnegut
• Gene: Gimap1 Location: Chr6:48715988-48720729 bp, + strand Genetic Position: Chr6, 23.69 cM, cytoband B
• Alliance: Gimap1^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced G to T transversion at base pair 48,743,098 (v38) on chromosome 6, or base pair 4,052 in the GenBank genomic region NC_000072 encoding Gimap1. The mutation corresponds to residue 808 in the mRNA sequence NM_008376 within exon 3 of 3 total exons. The mutation results in a glycine to tryptophan substitution at position 215 (G215W) in the GIMAP1 protein. (J:267546)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gimap1 Mutation: 8 strains or lines available

References

• Original: J:267546 Zhong X, et al., Mutagenetix entry for vonnegut. MGI Direct Data Submission. 2018
• All: 1 reference(s)