Yap1^M1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Yap1^M1Btlr
• Name: yes-associated protein 1; mutation 1, Bruce Beutler
• MGI ID: MGI:6268758
• Synonyms: Puddel_hunde
• Gene: Yap1 Location: Chr9:7932000-8004597 bp, - strand Genetic Position: Chr9, 2.46 cM
• Alliance: Yap1^M1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced G to A transition at base pair 8,004,284 (v38) on chromosome 9, or base pair 313 in the GenBank genomic region NC_000075 encoding Yap1. The mutation corresponds to residue 313 in the mRNA sequence NM_001171147 within exon 1 of 9 total exons. The mutation results in a glycine to aspartic acid substitution at amino acid 36 (G36D) in the YAP1 protein. (J:267549)
• Inheritance: Semidominant

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Yap1 Mutation: 38 strains or lines available

References

• Original: J:267549 McAlpine W, et al., Mutagenetix entry for Puddel_hunde. MGI Direct Data Submission. 2018
• All: 1 reference(s)