Psap^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Psap^m1Btlr
• Name: prosaposin; mutation 1, Bruce Beutler
• MGI ID: MGI:6268779
• Synonyms: twerk
• Gene: Psap Location: Chr10:60113449-60138376 bp, + strand Genetic Position: Chr10, 30.02 cM
• Alliance: Psap^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced T to G transversion at base pair 60,300,851 (v38) on chromosome 10, or base pair 23,224 in the GenBank genomic region NC_000076 encoding Psap. The mutation corresponds to residue 1,714 in the mRNA sequence NM_001146120 within exon 13 of 14 total exons. The mutation results in a cysteine to tryptophan substitution at amino acid 533 (C533W) in the PSAP protein. (J:267559)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Psap Mutation: 36 strains or lines available

References

• Original: J:267559 Prince L, et al., Mutagenetix entry for twerk. MGI Direct Data Submission. 2018
• All: 1 reference(s)