Ebf1^M4Btlr
Chemically induced Allele Detail

Summary

• Symbol: Ebf1^M4Btlr
• Name: early B cell factor 1; mutation 4, Bruce Beutler
• MGI ID: MGI:6268783
• Synonyms: Catastrophic
• Gene: Ebf1 Location: Chr11:44508144-44898918 bp, + strand Genetic Position: Chr11, 26.45 cM
• Alliance: Ebf1^M4Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced T to A transversion at base pair 44,883,885 (v38) on chromosome 11, or base pair 265,786 in the GenBank genomic region NC_000077. The mutation corresponds to residue 787 in the mRNA sequence NM_001290709 within exon 8 of 16 total exons. The mutation results in an asparagine to lysine substitution at position 236 (N236K) in the EBF1 protein. (J:267560)
• Inheritance: Dominant

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ebf1 Mutation: 74 strains or lines available

References

• Original: J:267560 Choi JH, et al., Mutagenetix entry for Catastrophic. MGI Direct Data Submission. 2018
• All: 1 reference(s)