Tcf12^M2Btlr
Chemically induced Allele Detail

Summary

• Symbol: Tcf12^M2Btlr
• Name: transcription factor 12; mutation 2, Bruce Beutler
• MGI ID: MGI:6269355
• Synonyms: Poorly2
• Gene: Tcf12 Location: Chr9:71751534-72019611 bp, - strand Genetic Position: Chr9, 39.85 cM
• Alliance: Tcf12^M2Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced T to A transversion at base pair 71,858,929 (v38) on chromosome 9, or base pair 252,891 in the GenBank genomic region NC_000075. The mutation corresponds to residue 1,759 in the mRNA sequence NM_011544 within exon 17 of 21 total exons. The mutation results in a valine to aspartic acid substitution at residue 498 (V498D) in the HEB protein. (J:267666)
• Inheritance: Semidominant

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tcf12 Mutation: 75 strains or lines available

References

• Original: J:267666 Choi JH, et al., Mutagenetix entry for Poorly2. MGI Direct Data Submission. 2018
• All: 1 reference(s)