Fbp1^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Fbp1^m1Btlr
• Name: fructose bisphosphatase 1; mutation 1, Bruce Beutler
• MGI ID: MGI:6269410
• Synonyms: fruko
• Gene: Fbp1 Location: Chr13:63012567-63036096 bp, - strand Genetic Position: Chr13, 32.74 cM, cytoband B3-C1
• Alliance: Fbp1^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced T to C transition at base pair 62,875,261 (v38) on chromosome 13, or base pair 13,038 in the GenBank genomic region NC_000079 encoding Fbp1. The mutation corresponds to residue 460 in the NM_019395 mRNA sequence in exon 2 of 7 total exons. The mutation results in a leucine (L) to proline (P) substitution at residue 74 (L74P) in the FBP1 protein. (J:267693)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fbp1 Mutation: 26 strains or lines available

References

• Original: J:267693 Ochoa CD, et al., Mutagenetix entry for fruko. MGI Direct Data Submission. 2018
• All: 1 reference(s)