Il2rb^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Il2rb^m1Btlr
• Name: interleukin 2 receptor, beta chain; mutation 1, Bruce Beutler
• MGI ID: MGI:6269414
• Synonyms: flybase
• Gene: Il2rb Location: Chr15:78363456-78379471 bp, - strand Genetic Position: Chr15, 37.52 cM, cytoband E
• Alliance: Il2rb^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced T to C transition at base pair 78,491,848 (v38) on chromosome 15, or base pair 19,774 in the GenBank genomic region NC_000081 encoding Il2rb. The mutation corresponds to residue 151 in the mRNA sequence NM_008368 within exon 2 of 10 total exons. The mutation results in a methionine to threonine substitution at position 1 (M1T) in the IL2RB protein. (J:267694)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Il2rb Mutation: 45 strains or lines available

References

• Original: J:267694 Zhong X, et al., Mutagenetix entry for flybase. MGI Direct Data Submission. 2018
• All: 1 reference(s)