Prkce^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Prkce^m1Btlr
• Name: protein kinase C, epsilon; mutation 1, Bruce Beutler
• MGI ID: MGI:6269444
• Synonyms: pinnacles
• Gene: Prkce Location: Chr17:86475213-86965347 bp, + strand Genetic Position: Chr17, 56.74 cM
• Alliance: Prkce^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced C to T transition at base pair 86,476,851 (v38) on chromosome 17, or base pair 309,298 in the GenBank genomic region NC_000083 encoding Prkce. The mutation corresponds to residue 1,461 in the mRNA sequence NM_011104 within exon 5 of 15 total exons. The mutation results in a threonine (T) to isoleucine (I) substitution at position 218 (T218I) in the PKC protein. (J:267703)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prkce Mutation: 40 strains or lines available

References

• Original: J:267703 Zhong X, et al., Mutagenetix entry for pinnacles. MGI Direct Data Submission. 2018
• All: 1 reference(s)