Zfp113^em1(IMPC)J
Endonuclease-mediated Allele Detail

Summary

• Symbol: Zfp113^em1(IMPC)J
• Name: zinc finger protein 113; endonuclease-mediated mutation 1, Jackson
• MGI ID: MGI:6272651
• Gene: Zfp113 Location: Chr5:138137964-138154006 bp, - strand Genetic Position: Chr5, 76.97 cM, cytoband G1
• Alliance: Zfp113^em1(IMPC)J page
• IMPC: Zfp113 gene page

Mutation origin

• Strain of Origin: C57BL/6NJ
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences GATGGACAGAATTAGAATTT and GGTAGATTGATTCCTAGCCC, which resulted in a 186 bp deletion beginning at Chromosome 5 position 138,151,134 bp and ending after 138,151,319 bp (GRCm38/mm10). This mutation deletes ENSMUSE00001226474 (exon 3) and 94 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 18 and early truncation 5 amino acids later. (J:188991)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Zfp113 Mutation: 26 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 2 reference(s)