Slc27a6^em1(IMPC)J
Endonuclease-mediated Allele Detail

Summary

• Symbol: Slc27a6^em1(IMPC)J
• Name: solute carrier family 27 (fatty acid transporter), member 6; endonuclease-mediated mutation 1, Jackson
• MGI ID: MGI:6272674
• Gene: Slc27a6 Location: Chr18:58689329-58745845 bp, + strand Genetic Position: Chr18, 33.71 cM
• Alliance: Slc27a6^em1(IMPC)J page
• IMPC: Slc27a6 gene page

Mutation origin

• Strain of Origin: C57BL/6NJ
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences GAGTTTGTAACCAGTGACCG and ATACGCTTTGTCCTGCAGCA, which resulted in a 424 bp deletion beginning at Chromosome 18 position 58,582,070 bp and ending after 58,582,493 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000362415(exon 4) and 299 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 281 and early truncation 19 amino acids later. (J:188991)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Slc27a6 Mutation: 42 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 3 reference(s)