Gt(ROSA)26Sor^tm3Ksvo
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^tm3Ksvo
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 3, Keral Svoboda
• MGI ID: MGI:6273506
• Synonyms: GtACR1-ts-FRed-Kv2.1
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^tm3Ksvo page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:284522
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S6/SvEvTac and C57BL/6J

Mutation description

• Allele Type: Targeted (Conditional ready, Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Mutation details: The targeting construct contains: a loxP-flanked neomycin cassette and GtACR1 (Guillardia theta anion channel rhodopsin 1) fused to FusionRed fluorescent protein (Fred) and the Kcnb1 soma trafficking domain followed by WPRE and polyA. (J:284522)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1040 strains or lines available

References

• Original: J:284522 Li N, et al., Spatiotemporal constraints on optogenetic inactivation in cortical circuits. Elife. 2019 Nov 18;8:e48622
• All: 8 reference(s)