Gucy2e^cpfl9
Spontaneous Allele Detail

Summary

• Symbol: Gucy2e^cpfl9
• Name: guanylate cyclase 2e; cone photoreceptor function loss mutation 9
• MGI ID: MGI:6274710
• Gene: Gucy2e Location: Chr11:69108943-69127862 bp, - strand Genetic Position: Chr11, 42.51 cM
• Alliance: Gucy2e^cpfl9 page

Mutation origin

• Strain of Origin: B6;129P2-Foxl2^{tm1(GFP/cre/ERT2)Pzg}/J

Mutation description

• Allele Type: Spontaneous (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This spontaneous 25 bp deletion in exon 11 is predicted to cause a frame shift and premature termination. (J:269362)
• Inheritance: Recessive

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gucy2e Mutation: 45 strains or lines available

References

• Original: J:269362 Chang B, et al., A new mouse model of cone photoreceptor function loss (cpfl9) with cone photoreceptor degeneration. Invest Ophthalmol Vis Sci. 2016;57(12):3150
• All: 2 reference(s)