Mir214^tm1.1Eno
Targeted Allele Detail

Summary

• Symbol: Mir214^tm1.1Eno
• Name: microRNA 214; targeted mutation 1.1, Eric N Olson
• MGI ID: MGI:6275029
• Gene: Mir214 Location: Chr1:162050937-162051046 bp, + strand Genetic Position: Chr1, 70.07 cM
• Alliance: Mir214^tm1.1Eno page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:184550
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The pre-microRNA was floxed. Cre-mediated recombination removed the FRT-flanked neomycin resistance cassette and microRNA sequence. Expression of the host gene Dnm3os is not affected. (J:184550)

Expression

In Mice Carrying this Mutation:	2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mir214 Mutation: 1 strain or line available

References

• Original: J:184550 Aurora AB, et al., MicroRNA-214 protects the mouse heart from ischemic injury by controlling Ca(2)(+) overload and cell death. J Clin Invest. 2012 Apr 2;122(4):1222-32
• All: 6 reference(s)