Lpar6^tm1.1Sati
Targeted Allele Detail

Summary

• Symbol: Lpar6^tm1.1Sati
• Name: lysophosphatidic acid receptor 6; targeted mutation 1.1, Satoshi Ishii
• MGI ID: MGI:6276060
• Synonyms: Lpa6^-
• Gene: Lpar6 Location: Chr14:73475331-73477798 bp, + strand Genetic Position: Chr14, 38.75 cM
• Alliance: Lpar6^tm1.1Sati page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:253134
• Parent Cell Line: B6-3i/HK3i (ES Cell)
• Strain of Origin: C57BL/6NJcl

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Cre-mediated recombination of loxP sites that flanked the entire coding region resulted in a deletion of the gene. RT-PCR analysis confirmed the absence of expression in the spleen of homozygous mutant mice. (J:253134)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lpar6 Mutation: 32 strains or lines available

References

• Original: J:253134 Hata E, et al., Lysophosphatidic acid receptors LPA4 and LPA6 differentially promote lymphocyte transmigration across high endothelial venules in lymph nodes. Int Immunol. 2016 Jun;28(6):283-92
• All: 3 reference(s)