Mtss1^tm1.1Oro
Targeted Allele Detail

Summary

• Symbol: Mtss1^tm1.1Oro
• Name: MTSS I-BAR domain containing 1; targeted mutation 1.1, Anthony E Oro
• MGI ID: MGI:6276624
• Synonyms: MIM^EX15
• Gene: Mtss1 Location: Chr15:58813083-58953854 bp, - strand Genetic Position: Chr15, 25.09 cM
• Alliance: Mtss1^tm1.1Oro page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:268944
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6 x 129/Sv

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exon 15, encoding the endophilin/Src-interacting domain, was floxed. Flp-mediated recombination removed the selection cassette. (J:268944)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Mtss1 Mutation: 120 strains or lines available

References

• Original: J:268944 Brown AS, et al., MTSS1/Src family kinase dysregulation underlies multiple inherited ataxias. Proc Natl Acad Sci U S A. 2018 Dec 26;115(52):E12407-E12416
• All: 1 reference(s)