Serpina5^em1(IMPC)Mbp
Endonuclease-mediated Allele Detail

Summary

• Symbol: Serpina5^em1(IMPC)Mbp
• Name: serine (or cysteine) peptidase inhibitor, clade A, member 5; endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
• MGI ID: MGI:6276941
• Gene: Serpina5 Location: Chr12:104067372-104072396 bp, + strand Genetic Position: Chr12, 53.3 cM, cytoband F1
• Alliance: Serpina5^em1(IMPC)Mbp page
• IMPC: Serpina5 gene page

Mutation origin

• Strain of Origin: C57BL/6NCrl
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele from IMPC was generated at UC Davies by injecting CAS9 Protein and 2 guide sequences GACAGGCCCATAAAAGGTTCAGG, CCTCAGGCAGTGAGCTAGCTCCA, which resulted in a Exon Deletion. (J:265051)
• Inheritance: Not Specified

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Serpina5 Mutation: 23 strains or lines available

References

• Original: J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023
• All: 3 reference(s)