Rtn1^tm1Yanr
Targeted Allele Detail

Summary

• Symbol: Rtn1^tm1Yanr
• Name: reticulon 1; targeted mutation 1, Riqiang Yan
• MGI ID: MGI:6277151
• Gene: Rtn1 Location: Chr12:72258526-72455828 bp, - strand Genetic Position: Chr12, 30.2 cM, cytoband C3
• Alliance: Rtn1^tm1Yanr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:247602
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A genomic region including exons 4 - 7 was replaced with a neo cassette via homologous recombination. (J:247602)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rtn1 Mutation: 39 strains or lines available

References

• Original: J:247602 Shi Q, et al., RTN1 and RTN3 protein are differentially associated with senile plaques in Alzheimer's brains. Sci Rep. 2017 Jul 21;7(1):6145
• All: 2 reference(s)