1700093K21Rik^em1(IMPC)J
Endonuclease-mediated Allele Detail

Summary

• Symbol: 1700093K21Rik^em1(IMPC)J
• Name: RIKEN cDNA 1700093K21 gene; endonuclease-mediated mutation 1, Jackson
• MGI ID: MGI:6278519
• Gene: 1700093K21Rik Location: Chr11:23466203-23471155 bp, - strand Genetic Position: Chr11, 14.32 cM, cytoband A3.3
• Alliance: 1700093K21Rik^em1(IMPC)J page
• IMPC: 1700093K21Rik gene page

Mutation origin

• Strain of Origin: C57BL/6NJ
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences GTAAGAATGAAAGCTAACAG and GTCCTAGCCATTATTATTTG, which resulted in a 389 bp deletion beginning at Chromosome 11 position 23,517,072 bp and ending after 23,517,460 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000103081 (exon 4) and 220 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 85 and early truncation 22 amino acids later. (J:188991)
• Inheritance: Not Specified

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any 1700093K21Rik Mutation: 18 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 3 reference(s)