Smg8^em1(IMPC)Bay
Endonuclease-mediated Allele Detail

Summary

• Symbol: Smg8^em1(IMPC)Bay
• Name: SMG8 nonsense mediated mRNA decay factor; endonuclease-mediated mutation 1, Baylor College of Medicine
• MGI ID: MGI:6279899
• Gene: Smg8 Location: Chr11:86968558-86977600 bp, - strand Genetic Position: Chr11, 51.89 cM, cytoband C
• Alliance: Smg8^em1(IMPC)Bay page
• IMPC: Smg8 gene page

Mutation origin

• Strain of Origin: C57BL/6NJ
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele from IMPC was generated at Bayor College of Medicine by injecting CAS9 Protein and 4 guide sequences CCCTTGTTCTTTATCACTGCGGT, CTTTATCACTGCGGTTGTGTTGG, GTGCAAGTGTGGCAATCTGGAGG, CCTGGGGCCTCCTCACTCATAGC, which resulted in a Exon Deletion. (J:265051)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Smg8 Mutation: 31 strains or lines available

References

• Original: J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023
• All: 3 reference(s)